Barriers-on-chips: Measurement of barrier function of tissues in organs-on-chips
نویسندگان
چکیده
منابع مشابه
3D Printing of Organs-On-Chips
Organ-on-a-chip engineering aims to create artificial living organs that mimic the complex and physiological responses of real organs, in order to test drugs by precisely manipulating the cells and their microenvironments. To achieve this, the artificial organs should to be microfabricated with an extracellular matrix (ECM) and various types of cells, and should recapitulate morphogenesis, cell...
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Trans-epithelial electrical resistance (TEER) is broadly used as an experimental readout and a quality control assay for measuring the integrity of epithelial monolayers cultured under static conditions in vitro, however, there is no standard methodology for its application to microfluidic organ-on-a-chip (organ chip) cultures. Here, we describe a new microfluidic organ chip design that contain...
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ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2018
ISSN: 1932-1058
DOI: 10.1063/1.5023041